Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 data for polymerid = 50001131
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mus musculus)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50582730(CHEMBL5087055)
Affinity DataIC50:  11nMAssay Description:Inhibition of LRRK2-WT in C57BL/6 mouse brain at 10 to 150 mg/kg and measured after 1 hrs by western blottingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mus musculus)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50582730(CHEMBL5087055)
Affinity DataIC50:  16nMAssay Description:Inhibition of LRRK2-WT-pSER935 in C57BL/6 mouse brain at 10 to 150 mg/kg and measured after 1 hrs by western blottingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mus musculus)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50582731(CHEMBL5092087)
Affinity DataIC50:  22nMAssay Description:Inhibition of LRRK2-WT in C57BL/6 mouse brain at 10 to 150 mg/kg and measured after 1 hrs by western blottingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mus musculus)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50582731(CHEMBL5092087)
Affinity DataIC50:  23nMAssay Description:Inhibition of LRRK2-WT-pSER935 in C57BL/6 mouse brain at 10 to 150 mg/kg and measured after 1 hrs by western blottingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed